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KMID : 0380020090240060570
Korean Journal of Biotechnology and Bioengineering
2009 Volume.24 No. 6 p.570 ~ p.578
Physiological Activity of Astaxanthin and its Inclusion Complex with Cyclodextrin
Kim So-Young

Cho Eun-Ah
Yoo Gui-Jae
Yoo Ji-Min
Son Seok-Min
In Man-Jin
Kim Dong-Chung
Chae Hee-Jeong
Abstract
In vitro biological activities such as antioxidant, whitening, anti-hangover and anticancer activities were evaluated. The antioxidant activities of astaxanthin and H. pluvialis extract were significantly higher than that of ¥á-tocopherol when the antioxidant activities were determined as xanthine oxidase inhibition, hydroxyl radical scavenging and DPPH radical scavenging. The whitening effect of H. pluvialis extract was about two times as kojic acid. H. pluvialis extract indicated an anticancer activity on a cervical cancer cell line. Astaxanthin showed anti-hangover effect of 1.5 times as jiguja extract. The anti-hangover effect of the inclusion complex (As-¥â-CD) was about 1.2 times of jiguja extract. And, the inclusion complex of Haematococcus pluvialis (H.p.-¥â-CD) showed almost the same whitening effect as kojic acid.
KEYWORD
Astaxanthin, Haematococcus pluvialis, Inclusion complex, biological activity
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